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Melanotan 2
- Research Grade
- 99% Purity
- Third-Party Verified
Availability: In stock
Melanotan 2
R600,00
Melanocortin peptide — studied for skin pigmentation and melanocortin receptor activity
Also available as a pre-filled Research Pen: 10mg.
Availability: In stock
Complimentary Purchase Kit
Every qualifying vial includes a complimentary purchase kit at no additional cost.
Research Overview
About Melanotan 2
Melanotan-2 is a synthetic cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone (α-MSH).
How It Works in Research
Research indicates that Melanotan-2 activates melanocortin receptors (MC1R, MC3R, MC4R), triggering increased melanin production in skin cells. Studies also show activity at receptors involved in appetite regulation and reproductive function pathways.
Research Applications
Skin pigmentation: Studied for its ability to stimulate melanin production and increase skin pigmentation through UV-independent pathways. Photoprotection: Researched for its potential role in protecting skin cells from UV-induced damage through enhanced melanogenesis. Appetite and reproductive function: Observed in research to interact with MC3R and MC4R receptors involved in appetite regulation and sexual function pathways.
Functional Performance Profile
Key Benefits
- Melanogenesis Support
- Libido Enhancement
- Photoprotection
Product Specifications
- Purity: 99.5%
- Form: Lyophilized peptide
- Storage: 2-9°C Refrigerated
Research Information
- Type: Melanocortin analog
- Focus: Melanogenesis and libido
Scientific Information
Scientific Studies (PubMed)
Research Reference Parameters — Laboratory Use Only
- Initial phase: 0.25-0.5 mg daily (loading phase)
- Standard research range: 0.5-1.0 mg 2-3 times per week (maintenance)
- Advanced research range: 1.0 mg as needed (maintenance)
- Loading phase: 1-2 weeks | Maintenance: ongoing as needed
Mechanism of Action
MT-II activates MC1R receptors in melanocytes, triggering melanin synthesis without UV damage. MC4R activation in the hypothalamus suppresses appetite and increases energy expenditure. MC3R/MC4R effects in neural pathways enhance sexual arousal and function.
Key Research Characteristics
Melanocortin Receptor Agonist
Melanotan II is a synthetic analog of alpha-melanocyte stimulating hormone (α-MSH) that binds to melanocortin receptors MC1R (tanning), MC3R, and MC4R (appetite and arousal).
Photoprotective Melanogenesis
Stimulates natural melanin production without UV exposure, providing a 'base tan' that offers sun protection before UV exposure occurs - a unique photoprotective mechanism.
Multi-Receptor Activity
Unlike MT-I, MT-II affects multiple melanocortin receptors, explaining its broader effects on tanning, appetite, and sexual function.
Potential Benefits in Research
Photoprotection & Tanning
- UV-independent melanin production and tanning
- Reduced sunburn risk through increased melanin
- Even, natural-looking tan development
- Protection for those who cannot tan naturally
- Appetite & Body Composition
- Reduced appetite through MC4R activation
- Decreased food intake in research subjects
- Potential body weight reduction
- Improved eating behavior control
- Sexual Function
- Enhanced libido in both male and female subjects
- Improved erectile function markers
- Increased sexual arousal and desire
- Better sexual satisfaction scores
Safety Profile
Important: These side effects are reported from research studies and may vary by individual, dosage, and protocol. Always monitor subjects carefully and consult with qualified researchers.
Nausea (most common, especially initial doses)
- Flushing and facial warmth
- Spontaneous erections in males
- Increased libido
- Darkening of moles and freckles
- Appetite suppression
- Possible stretching/yawning
- Rare: hyperpigmentation with prolonged use
Research Applications
REFERENCE RECONSTITUTION INFORMATION
RECOMMENDED RECONSTITUTION GUIDE This guide explains how research peptides are commonly reconstituted using bacteriostatic water (BAC water), and shows how dosing volumes correspond to syringe units. Always follow sterile preparation techniques when handling research peptides.
Always follow sterile preparation techniques when handling research peptides.
General Preparation
- Use bacteriostatic water (BAC water) only
- Inject water slowly down the inside of the vial
- Do not shake the vial
- Gently swirl to dissolve the peptide powder
- Store refrigerated after mixing
- Use sterile technique when handling
MELANOTAN 2 (10mg) - RECONSTITUTION TABLES
Reference Handling Information
Reference information for laboratory handling of Melanotan 2.
- Route
- Subcutaneous injection
- Schedule
- Any consistent time
- Injection Sites
- Rotate injection sites (abdomen, thighs, upper arms)
- Use sterile technique when handling and administering
- Cycle: 6–8 weeks loading phase, then maintenance dosing 1–2× weekly
- Goal: Increase skin pigmentation (tanning) through melanocortin receptor activation
Reference Parameters (Dosing Protocol (2ml BAC Water; 5.00 mg/ml))
| WEEK | DOSE PER INJECTION | UNITS (PER INJECTION) (ML) |
|---|---|---|
| Week 1 | 0.25 mg | 5 units (0.05ml) |
| Week 2-4 | 0.50 mg | 10 units (0.10ml) |
| Maintenance | 0.50–1.00 mg (1–2× weekly) | 10–20 units (0.10–0.20ml) |
Reference Parameters (Dosing Protocol (3ml BAC Water; 3.33 mg/ml))
| WEEK | DOSE PER INJECTION | UNITS (PER INJECTION) (ML) |
|---|---|---|
| Week 1 | 0.25 mg | 7.5 units (0.075ml) |
| Week 2-4 | 0.50 mg | 15 units (0.15ml) |
| Maintenance | 0.50–1.00 mg (1–2× weekly) | 15–30 units (0.15–0.30ml) |
Experimental Study Period
View Certificate of Analysis
View Certificate of Analysis Each batch of Melanotan 2 is independently tested by third-party laboratories. Download the Certificate of Analysis to verify purity, identity, and quality.
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FOR RESEARCH PURPOSES ONLY
This product is intended for research and laboratory use only. Always consult qualified researchers and follow appropriate safety protocols.






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