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Cortagen
- Research Grade
- 99% Purity
- Third-Party Verified
Cortagen
Cortagen is a synthetic tetrapeptide bioregulator (Ala-Glu-Asp-Pro) investigated for its potential neuroprotective, neuroregenerative and cognitive-supporting properties. It is studied in laboratory research involving neuronal health, ageing and tissue repair.
Complimentary Purchase Kit
Every qualifying vial includes a complimentary purchase kit at no additional cost.
Research Overview
About Cortagen
Cortagen belongs to the Khavinson peptide bioregulator family. It has been investigated for its ability to influence gene expression, support neuronal repair mechanisms and promote healthy nervous system function. Research has focused on neuroprotection, cognitive performance and recovery following neural injury.
How It Works in Research
Cortagen (Ala-Glu-Asp-Pro) is a synthetic tetrapeptide derived from Cortexin. Research suggests it modulates gene expression involved in neuronal differentiation, growth and stress resistance, while promoting neurotrophic signalling, reducing oxidative stress and supporting peripheral nerve regeneration.
Research Applications
• Neuroprotection • Cognitive function • Memory • Peripheral nerve regeneration • Healthy ageing • Cellular repair
Product Specifications
- Product Name: Cortagen
- Alternate Chemical Name: AEDP
- CAS Number: 335591-03-2
- Molecular Formula: C17H26N4O9
- Molecular Weight: 430.41 g/mol
Research Information
- Amino Acid Sequence: Ala-Glu-Asp-Pro
- Reference Strength: 20 mg
- Appearance: White to off-white lyophilised powder
- Purity Standard: ≥98% (HPLC)
- Category: Neuroregulatory Tetrapeptide
- Storage: 2–8°C after reconstitution
Mechanism of Action
Cortagen (Ala-Glu-Asp-Pro) is a synthetic tetrapeptide derived from Cortexin. Research suggests it modulates gene expression involved in neuronal differentiation, growth and stress resistance, while promoting neurotrophic signalling, reducing oxidative stress and supporting peripheral nerve regeneration.
Potential Benefits in Research
Research suggests potential support for peripheral nerve regeneration, cognitive performance, memory, neuronal resilience, oxidative stress reduction and healthy ageing.
Safety Profile
Published research has generally reported good tolerability. Mild injection-site irritation may occur. Long-term human safety data remain limited.
Research Applications
REFERENCE RECONSTITUTION INFORMATION
Goal: Support neural regeneration, cognitive function and cellular repair. Schedule: Once daily using a 5 days on / 2 days off protocol. Cycle Length: 4 weeks standard; may be extended to 8 weeks if desired. Dose Range: 1–2 mg daily. Reconstitution: Add 3.0 mL bacteriostatic water to one 20 mg vial (6.67 mg/mL).
Always follow sterile preparation techniques when handling research peptides.
General Preparation
- Using a sterile syringe, slowly add 3.0 mL bacteriostatic water down the vial wall. Allow the powder to dissolve naturally and gently swirl until clear. Do not shake vigorously.
CORTAGEN (20MG)- RECONSTITUTION TABLES
Reference Handling Information
Reference information for laboratory handling of Cortagen.
- Schedule: Once daily using a 5 days on / 2 days off protocol.
Reference Parameters (Dosing Protocol)
| Week | Daily Dose | U-100 Units | Volume | Frequency |
|---|---|---|---|---|
| Weeks 1–2 | 1 mg | 15 units | 0.15 mL | 5 days on / 2 days off |
| Weeks 3–4 | 2 mg | 30 units | 0.30 mL | 5 days on / 2 days off |
Experimental Study Period
View Certificate of Analysis
View Certificate of Analysis Each batch of Cortagen is independently tested by third-party laboratories. Download the Certificate of Analysis to verify purity, identity, and quality.
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FOR RESEARCH PURPOSES ONLY
This product is intended for research and laboratory use only. Always consult qualified researchers and follow appropriate safety protocols.

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